Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo
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Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo
The number of myelin sheaths made by individual oligodendrocytes regulates the extent of myelination, which profoundly affects central nervous system function. It remains unknown when, during their life, individual oligodendrocytes can regulate myelin sheath number in vivo. We show, using live imaging in zebrafish, that oligodendrocytes make new myelin sheaths during a period of just 5 hr, with...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2013
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2013.05.013